논문현황

SMUP-Cell | 2021-01-03
Senescence-Associated Secretory Phenotype Suppression Mediated by Small-Sized Mesenchymal Stem Cells Delays Cellular Senescence through TLR2 and TLR5 Signaling.
작은 사이즈의 제대혈 유래 줄기세포이 SASP 활성화와 연관된 TLR2 및 TLR5 신호전달을 억제시켜, 세포노화를 지연시킴.

· 발행정보 | Cells. 2021 Jan 3;10(1):63. doi: 10.3390/cells10010063.
· 저자 | Ji Hye Kwon, Miyeon Kim, Soyoun Um, Hyang Ju Lee, Yun Kyung Bae, Soo Jin Choi, Hyun Ho Hwang, Wonil Oh, Hye Jin Jin
줄기세포 | 2020-12-26
Prospects for the therapeutic development of umbilical cord blood-derived mesenchymal stem cells.
다양한 질환 내 사용되고 있는 제대혈 유래 줄기세포의 우수성 및 치료제로서의 가능성에 관한 리뷰논문.

· 발행정보 | World J Stem Cells. 2020 Dec 26;12(12):1511-1528. doi: 10.4252/wjsc.v12.i12.1511.
· 저자 | Soyoun Um, Jueun Ha, Soo Jin Choi, Wonil Oh, Hye Jin Jin
카티스템 | 2020-10-17
Allogeneic umbilical cord blood-derived mesenchymal stem cells combined with high tibial osteotomy: a retrospective study on safety and early results
무릎 내측부 골관절염 환자에서 HTO와 결합된 카티스템 투여는 안전하며, 연골상태 개선을 나타냄.

· 발행정보 | Int Orthop. 2021 Feb;45(2):481-488. doi: 10.1007/s00264-020-04852-y.
· 저자 | Young-Woo Chung, Hong-Yeol Yang, Sung-Ju Kang, Eun-Kyoo Song, Jong-Keun Seon
카티스템 | 2020-07-27
Comparison of Bone Marrow Aspirate Concentrate and Allogenic Human Umbilical Cord Blood Derived Mesenchymal Stem Cell Implantation on Chondral Defect of Knee: Assessment of Clinical and Magnetic Resonance Imaging Outcomes at 2-Year Follow-Up
BMAC 및 카티스템 투여 모두 2년 F/U에서 무릎 연골결손상의 연골병변 치료에 안전하고 효과적임을 확인함.

· 발행정보 | Cell Transplant. 2020 Jan-Dec;29:1-10. doi: 10.1177/0963689720943581.
· 저자 | Dong Jin Ryu, Yoon Sang Jeon, Jun Sung Park, Gi Cheol Bae, Jeong-Seok Kim, Myung Ku Kim
줄기세포 | 2020-07-18
Galectin-3 Secreted by Human Umbilical Cord Blood-Derived Mesenchymal Stem Cells Reduces Aberrant Tau Phosphorylation in an Alzheimer Disease Model
hUCB-MSCs 및 hUCB-MSCs 분비단백질 Galectin-3가 알츠하이머병 모델에서 비정상 타우 과인산화를 감소시킬 수 있음을 제시함.

· 발행정보 | Stem Cells Int. 2020 Jul 18;2020:8878412.doi:10.1155/2020/8878412
· 저자 | Hoon Lim, Dahm Lee, Wan Kyu Choi, Soo Jin Choi, Wonil Oh, Dong Hyun Kim
카티스템 | 2020-06-26
High tibial osteotomy with human umbilical cord blood-derived mesenchymal stem cells implantation for knee cartilage regeneration
HTO와 병용하는 카티스템 투여는 내측부 골관절염 및 내반변형 환자에서 연골재생을 향상시키는 효과적인 치료법임.

· 발행정보 | World J Stem Cells. 2020 Jun 26;12(6):514-526. doi: 10.4252/wjsc.v12.i6.514.
· 저자 | Jun-Seob Song, Ki-Taek Hong, Chae-Gwan Kong, Na-Min Kim, Jae-Yub Jung, Han-Soo Park, Young Ju Kim, Ki Bong Chang, Seok Jung Kim
기타 | 2020-05-28
Migration Inhibitory Factor in Conditioned Medium from Human Umbilical Cord Blood-Derived Mesenchymal Stromal Cells Stimulates Hair Growth
제대혈 유래 줄기세포 내 배양에 의한 모발 증식과 최적화 배양액 생산 방법 제시

· 발행정보 | Cells, 2020 May 28;9(6):1344. doi: 10.3390/cells9061344.
· 저자 | Hyun Ah Oh, Jihye Kwak, Beom Joon Kim, Hye Jin Jin, Won Seok Park, Soo Jin Choi, Wonil Oh, Soyoun Um
SMUP-Cell | 2020-04-28
A Small-Sized Population of Human Umbilical Cord Blood-Derived Mesenchymal Stem Cells Shows High Stemness Properties and Therapeutic Benefit
작은 사이즈의 제대혈 유래 줄기세포가 폐기종 동물모델에서 우수한 치료효능을 보임.

· 발행정보 | Stem Cells Int. 2020 Apr 28;2020:5924983. doi: 10.1155/2020/5924983.
· 저자 | Miyeon Kim, Yun Kyung Bae, Soyoun Um, Ji Hye Kwon, Gee-Hye Kim, Soo Jin Choi, Wonil Oh, Hye Jin Jin
줄기세포 | 2020-04-17
Primary cilia mediate Wnt5a/β-catenin signaling to regulate adipogenic differentiation of human umbilical cord blood-derived mesenchymal stem cells following calcium induction
칼슘처리에 따라 UCB-MSC내 Wnt5a/β-catenin 신호전달되며, 이는 섬모생성을 유도하여 지방분화를 촉진시킴.

· 발행정보 | Tissue Eng Regen Med. 2020 Apr;17(2):193-202. doi: 10.1007/s13770-019-00237-4.
· 저자 | Yun Kyung Bae, Gee-Hye Kim, Ji Hye Kwon, Miyeon Kim, Soo Jin Choi, Wonil Oh, Soyoun Um, Hye Jin Jin
카티스템 | 2020-01-24
Human umbilical cord blood-derived mesenchymal stem cell implantation for osteoarthritis of the knee
카티스템 투여는 60세 이상의 무릎 내측부 골관절염 환자에서 연골을 잘 재생시킴과 더불어 만족스러운 임상결과를 나타냄.

· 발행정보 | Arch Orthop Trauma Surg. 2020 Apr;140(4):503-509. doi: 10.1007/s00402-020-03349-y.
· 저자 | Jun-Seob Song, Ki-Taek Hong, Na-Min Kim, Han-Soo Park , Nam-Hong Choi